A novel antimicrobial coating to prevent periprosthetic joint infection

Prevention of Periprosthetic Joint Infection

Prosthetic joint infection (PJI) is a calamitous complication with high morbidity and substantial cost. The reported incidence is low but it is probably underestimated due to the difficulty in diagnosis. PJI has challenged the orthopaedic community for several years and despite all the advances in this field, it is still a real concern with immense impact on patients, and the healthcare system....

prevention of periprosthetic joint infection

prosthetic joint infection (pji) is a calamitous complication with high morbidity and substantial cost. the reported incidence is low but it is probably underestimated due to the difficulty in diagnosis. pji has challenged the orthopaedic community for several years and despite all the advances in this field, it is still a real concern with immense impact on patients, and the healthcare system....

Prevention of Periprosthetic Joint Infection

Prosthetic joint infection (PJI) is a calamitous complication with high morbidity and substantial cost. The reported incidence is low but it is probably underestimated due to the difficulty in diagnosis. PJI has challenged the orthopaedic community for several years and despite all the advances in this field, it is still a real concern with immense impact on patients, and the healthcare system....

In vivo efficacy of a silicone‒cationic steroid antimicrobial coating to prevent implant-related infection.

Active release antimicrobial coatings for medical devices have been developed to prevent and treat biofilm implant-related infections. To date, only a handful of coatings have been put into clinical use, with limited success. In this study, a novel antimicrobial compound was incorporated into a silicone (polydimethylsiloxane or PDMS) polymer to develop a novel active release coating that addres...

Definition of periprosthetic joint infection.